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Query: GM2A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GM2A 0 0.422 1.660 -0.700

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GM2A Ubiquitylation K179 0.422 _IESVLSSSGK(gl)R_

Background Information for GM2A:


Pubmed-GM2A »
Uniprot-GM2A »
Biogrid-GM2A »
ProteomicsDB-GM2A »

Tumorportal-GM2A »
COSMIC-GM2A »
GenomeRNAi-GM2A »
Genecards-GM2A


Protein-protein Interactions for GM2A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AIRE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C21orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC51 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM60A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FTH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GM2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GMCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIR3DS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDE4DIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SF3A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSBP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VNN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZIC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GM2A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ML_dom IPR003172 0


Protein complexes (CORUM database) featuring GM2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GM2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0043085 positive regulation of catalytic activity Database 0.78
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0030149 sphingolipid catabolic process Database 0.32
Category members GO Category GO:0008047 enzyme activator activity Database 0.15
Category members GO Category GO:0043202 lysosomal lumen Database 0.07
Category members GO Category GO:0050885 neuromuscular process controlling balance Database 0.02
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_126 REACTOME_GLYCOSPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0001573 ganglioside metabolic process Database 0
Category members GO Category GO:0004563 beta-N-acetylhexosaminidase activity Database 0
Category members GO Category GO:0005319 lipid transporter activity Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0006687 glycosphingolipid metabolic process Database 0
Category members GO Category GO:0006689 ganglioside catabolic process Database 0
Category members GO Category GO:0006869 lipid transport Database 0
Category members GO Category GO:0007611 learning or memory Database 0
Category members GO Category GO:0009313 oligosaccharide catabolic process Database 0
Category members GO Category GO:0009898 cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0016004 phospholipase activator activity Database 0
Category members GO Category GO:0019377 glycolipid catabolic process Database 0
Category members GO Category GO:0019915 lipid storage Database 0
Category members GO Category GO:0045179 apical cortex Database 0
Category members GO Category GO:0050877 neurological system process Database 0
Category members GO Category GO:0051345 positive regulation of hydrolase activity Database 0


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