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Query: GJC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GJC1 0 0.679 0.340 -0.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GJC1 Ubiquitylation K391 0.221 0.458 _SGDGK(gl)TSVWI_

Background Information for GJC1:


Pubmed-GJC1 »
Uniprot-GJC1 »
Biogrid-GJC1 »
ProteomicsDB-GJC1 »

Tumorportal-GJC1 »
COSMIC-GJC1 »
GenomeRNAi-GJC1 »
Genecards-GJC1


Protein-protein Interactions for GJC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GJC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR114 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRPR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC18A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC22A16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPK1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZACN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GJC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Connexin IPR000500 0
Category members Connexin_N IPR013092 0
Category members Connexin_CCC IPR019570 0


Protein complexes (CORUM database) featuring GJC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GJC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0007267 cell-cell signaling Database 0.94
Category members GO Category GO:0014704 intercalated disc Database 0.64
Category members GO Category GO:0016264 gap junction assembly Database 0.35
Category members GO Category GO:0007043 cell-cell junction assembly Database 0.31
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0005216 ion channel activity Database 0.16
Category members Pathway Pathway_1267 REACTOME_GAP_JUNCTION_TRAFFICKING 0 0
Category members Pathway Pathway_1294 REACTOME_GAP_JUNCTION_ASSEMBLY 0 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0005243 gap junction channel activity Database 0
Category members GO Category GO:0005921 gap junction Database 0
Category members GO Category GO:0005922 connexon complex Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006936 muscle contraction Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0048468 cell development Database 0
Category members GO Category GO:0048738 cardiac muscle tissue development Database 0


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