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Query: FMR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FMR1 0 2.645 -0.041 0.382 -0.062 0.362
FMR1 0 2.645 0.713 -0.183 -0.136

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FMR1 Phosphorylation S601 0.394 0.422 _TDGS(ph)ISGDRQPVTVADYISR_
FMR1 Phosphorylation T598 0.270 _T(ph)DGSISGDRQPVTVADYISR_
FMR1 Ubiquitylation K207 0.059 _NEEASK(gl)QLESSR_
FMR1 Ubiquitylation K310 0.475 _LIQEIVDK(gl)SGVVR_
FMR1 Ubiquitylation K372 -0.085 _ENSTHFSQPNSTK(gl)VQR_

Background Information for FMR1:





Protein-protein Interactions for FMR1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCLAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait DENND6A Cat. description Hein, Mann, Cell 2015
Category members IP bait GBA Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF5B Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MZT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait SART3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait STMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBA6 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait FMR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBP2NL Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FMR1

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring FMR1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FMR1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0043198 dendritic shaft Database 0.93
Category members GO Category GO:0043197 dendritic spine Database 0.86
Category members GO Category GO:0042788 polysomal ribosome Database 0.28
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0005845 mRNA cap binding complex Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0045947 negative regulation of translational initiation Database 0
Category members GO Category GO:0071598 neuronal ribonucleoprotein granule Database 0


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