bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: FIP1L1

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FIP1L1 1 2.845 -1.930 3.940 0.293 -0.487 0.231 -0.419 0.354

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FIP1L1 Phosphorylation S492 0.040 0.085 _DHS(ph)PTPSVFNSDEER_
FIP1L1 Phosphorylation T494 0.134 0.020 _DHSPT(ph)PSVFNSDEER_
FIP1L1 Phosphorylation S259 -1.364 -0.698 _AEFTS(ph)PPSLFK_
FIP1L1 Ubiquitylation K123 -1.286 _TGAPQYGSYGTAPVNLNIK(gl)TGGR_

Background Information for FIP1L1:


Pubmed-FIP1L1 »
Uniprot-FIP1L1 »
Biogrid-FIP1L1 »
ProteomicsDB-FIP1L1 »

Tumorportal-FIP1L1 »
COSMIC-FIP1L1 »
GenomeRNAi-FIP1L1 »
Genecards-FIP1L1


Protein-protein Interactions for FIP1L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CPSF3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FIP1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2A Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait SYMPK Cat. description Hein, Mann, Cell 2015
Category members IP bait CPSF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPSF4L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FIP1L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_CSF1/PDGF_rcpt IPR016243 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring FIP1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1144 Cleavage and polyadenylation factor (CPSF) Database 0.01


Categories featuring FIP1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0005847 mRNA cleavage and polyadenylation specificity factor complex Database 0.11
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Disease phenotype HYPEREOSINOPHILIC_SYNDROME_IDIOPATHIC HYPEREOSINOPHILIC SYNDROME IDIOPATHIC Database 0
Category members Disease phenotype Idiopathic_hypereosinophilic_syndrome Idiopathic hypereosinophilic syndrome Database 0
Category members GO Category GO:0004714 transmembrane receptor protein tyrosine kinase activity Database 0
Category members GO Category GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


.

© Copyright Svejstrup Laboratory 2015