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Query: FGD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FGD1 0 1.146 -0.610 1.420

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FGD1 Phosphorylation S50 -0.140 -0.134 _RGSGS(ph)ALGGPLDPQFVGPSDTSLGAAPGHR_
FGD1 Phosphorylation S135 -0.194 _LRS(ph)DPGPPTETPSQRPSPLK_
FGD1 Phosphorylation S82 -0.199 _VLPCGPS(ph)PQHHR_
FGD1 Phosphorylation S116 -0.758 -0.450 _SLS(ph)LDPGQSLEPHPEGPQR_
FGD1 Phosphorylation S114 -0.776 -0.924 _S(ph)LSLDPGQSLEPHPEGPQR_
FGD1 Phosphorylation S954 -0.708 -1.116 _GDTFCPGPTLSEDREMEEAPVAALGATAEPPES(ph)PQTR_
FGD1 Phosphorylation S48 -0.284 _RGS(ph)GSALGGPLDPQFVGPSDTSLGAAPGHR_

Background Information for FGD1:


Pubmed-FGD1 »
Uniprot-FGD1 »
Biogrid-FGD1 »
ProteomicsDB-FGD1 »

Tumorportal-FGD1 »
COSMIC-FGD1 »
GenomeRNAi-FGD1 »
Genecards-FGD1


Protein-protein Interactions for FGD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FGD1 Cat. description Hein, Mann, Cell 2015


Protein Domains in FGD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members PH_domain IPR001849 0.14
Category members DH-domain IPR000219 0.05
Category members Znf_FYVE IPR000306 0
Category members Znf_FYVE-rel IPR017455 0


Protein complexes (CORUM database) featuring FGD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FGD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1140 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 0 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members Pathway Pathway_293 PID_CDC42_REG_PATHWAY 0 0.05
Category members GO Category GO:0043088 regulation of Cdc42 GTPase activity Database 0.03
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0031267 small GTPase binding Database 0
Category members GO Category GO:0046847 filopodium assembly Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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