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Query: FDFT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FDFT1 0 -0.534 -0.960 0.750 -0.161 -0.107 -0.241 -0.023 0.147

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FDFT1 Ubiquitylation K41 -0.022 _MDQDSLSSSLK(gl)TCYK_
FDFT1 Ubiquitylation K213 -0.200 _ANSMGLFLQK(gl)TNIIR_
FDFT1 Ubiquitylation K45 -0.877 -0.339 _TCYK(gl)YLNQTSR_
FDFT1 Ubiquitylation K115 -0.424 _FMESK(gl)EKDR_
FDFT1 Ubiquitylation K358 -2.436 -0.946 _IPDSDPSSSK(gl)TR_

Background Information for FDFT1:


Pubmed-FDFT1 »
Uniprot-FDFT1 »
Biogrid-FDFT1 »
ProteomicsDB-FDFT1 »

Tumorportal-FDFT1 »
COSMIC-FDFT1 »
GenomeRNAi-FDFT1 »
Genecards-FDFT1


Protein-protein Interactions for FDFT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CD97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FDFT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FDFT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Squ/phyt_synthse IPR002060 0
Category members Terpenoid_synth IPR008949 0


Protein complexes (CORUM database) featuring FDFT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FDFT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006694 steroid biosynthetic process Database 0.29
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members GO Category GO:0008610 lipid biosynthetic process Database 0.05
Category members Pathway Pathway_162 KEGG_STEROID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0008299 isoprenoid biosynthetic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0


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