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Query: FCHO2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FCHO2 0 2.540 0.030 -0.430

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FCHO2 Phosphorylation S403 0.527 0.628 _NLS(ph)NEELTK_
FCHO2 Phosphorylation S511 0.470 _AESSSS(ph)ISSSASLSAANTPTVGVSR_
FCHO2 Phosphorylation S394 -0.115 0.075 _HS(ph)PVQMNR_
FCHO2 Ubiquitylation K744 0.921 0.005 _LSSISEK(gl)SENGGSGSLR_
FCHO2 Phosphorylation S387 0.700 -0.080 _VSIGNITLS(ph)PAISR_
FCHO2 Phosphorylation S488 -1.543 -1.955 _LSGINEIPRPFS(ph)PPVTSNT(ph)SPPPAAPLAR_
FCHO2 Phosphorylation S478 -1.450 -2.102 _LS(ph)GINEIPRPFS(ph)PPVTSNTSPPPAAPLAR_
FCHO2 Ubiquitylation K103 1.207 _EVQK(gl)YGEEQVK_
FCHO2 Ubiquitylation K165 -1.342 _EIEK(gl)AAVK_
FCHO2 Phosphorylation T492 -1.785 _LTSGKLSGINEIPRPFSPPVT(ph)S(ph)NTSPPPAAPLAR_

Background Information for FCHO2:


Pubmed-FCHO2 »
Uniprot-FCHO2 »
Biogrid-FCHO2 »
ProteomicsDB-FCHO2 »

Tumorportal-FCHO2 »
COSMIC-FCHO2 »
GenomeRNAi-FCHO2 »
Genecards-FCHO2


Protein-protein Interactions for FCHO2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PICALM Cat. description Hein, Mann, Cell 2015
Category members IP bait AP2M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP2S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DAB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPC25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FCHO2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FCH_dom IPR001060 0
Category members Muniscin_C IPR018808 0


Protein complexes (CORUM database) featuring FCHO2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FCHO2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0005905 coated pit Database 0.17
Category members GO Category GO:0005546 phosphatidylinositol-4,5-bisphosphate binding Database 0.09
Category members GO Category GO:0010324 membrane invagination Database 0.09
Category members GO Category GO:0030136 clathrin-coated vesicle Database 0.06
Category members GO Category GO:0001786 phosphatidylserine binding Database 0
Category members GO Category GO:0048268 clathrin coat assembly Database 0


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