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Query: ETV5

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ETV5 0 1.268 -0.820 1.770

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ETV5 Phosphorylation S136 -0.502 _RELHS(ph)PSSELSSCSHEQALGANYGEK_

Background Information for ETV5:


Pubmed-ETV5 »
Uniprot-ETV5 »
Biogrid-ETV5 »
ProteomicsDB-ETV5 »

Tumorportal-ETV5 »
COSMIC-ETV5 »
GenomeRNAi-ETV5 »
Genecards-ETV5


Protein-protein Interactions for ETV5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ETV5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ETV5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ets_dom IPR000418 0.07
Category members ETS_PEA3_N IPR006715 0


Protein complexes (CORUM database) featuring ETV5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ETV5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_968 PID_FOXM1_PATHWAY 0 0.8
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0007610 behavior Database 0.04
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_901 BIOCARTA_IL12_PATHWAY 0 0
Category members Pathway Pathway_904 PID_IL12_STAT4_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007274 neuromuscular synaptic transmission Database 0
Category members GO Category GO:0007626 locomotory behavior Database 0
Category members GO Category GO:0034599 cellular response to oxidative stress Database 0
Category members GO Category GO:0045666 positive regulation of neuron differentiation Database 0
Category members GO Category GO:0048133 male germ-line stem cell division Database 0
Category members GO Category GO:0050807 regulation of synapse organization Database 0
Category members GO Category GO:0060252 positive regulation of glial cell proliferation Database 0
Category members GO Category GO:0060762 regulation of branching involved in mammary gland duct morphogenesis Database 0
Category members GO Category GO:0071340 skeletal muscle acetylcholine-gated channel clustering Database 0


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