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Query: EPN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPN2 0 1.046 -0.550 0.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPN2 Phosphorylation S172 -0.027 _GS(ph)SQPNLSTSHSEQEYGK_
EPN2 Phosphorylation S173 0.271 -0.203 _GSS(ph)QPNLSTSHSEQEYGK_
EPN2 Phosphorylation S192 -0.581 -0.207 _AGGS(ph)PASYHGSTSPR_
EPN2 Ubiquitylation K135 0.492 _QLVALLK(gl)DEER_

Background Information for EPN2:


Pubmed-EPN2 »
Uniprot-EPN2 »
Biogrid-EPN2 »
ProteomicsDB-EPN2 »

Tumorportal-EPN2 »
COSMIC-EPN2 »
GenomeRNAi-EPN2 »
Genecards-EPN2


Protein-protein Interactions for EPN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EPN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EPN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ENTH_VHS IPR008942 0.96
Category members Ubiquitin-int_motif IPR003903 0.49
Category members Epsin_dom_N IPR001026 0
Category members ANTH_dom IPR011417 0
Category members Epsin-like_N IPR013809 0


Protein complexes (CORUM database) featuring EPN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0030136 clathrin-coated vesicle Database 0.06
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0005543 phospholipid binding Database 0
Category members GO Category GO:0008289 lipid binding Database 0
Category members GO Category GO:0048568 embryonic organ development Database 0


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