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Query: EIF4EBP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF4EBP2 0 -0.324 1.140 -0.720

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EIF4EBP2 Phosphorylation T46 -0.240 -0.084 _TVAISDAAQLPHDYCTTPGGTLFSTT(ph)PGGTR_
EIF4EBP2 Phosphorylation T41 -0.111 _TVAISDAAQLPHDYCTTPGGT(ph)LFST(ph)TPGGTR_
EIF4EBP2 Phosphorylation T45 -0.113 _TVAISDAAQLPHDYCTTPGGT(ph)LFST(ph)TPGGTR_
EIF4EBP2 Phosphorylation Y34 -0.496 -0.320 _TVAISDAAQLPHDY(ph)CTTPGGTLFSTT(ph)PGGTR_
EIF4EBP2 Phosphorylation T37 -0.389 -0.339 _TVAISDAAQLPHDYCTT(ph)PGGTLFST(ph)TPGGTR_

Background Information for EIF4EBP2:


Pubmed-EIF4EBP2 »
Uniprot-EIF4EBP2 »
Biogrid-EIF4EBP2 »
ProteomicsDB-EIF4EBP2 »

Tumorportal-EIF4EBP2 »
COSMIC-EIF4EBP2 »
GenomeRNAi-EIF4EBP2 »
Genecards-EIF4EBP2


Protein-protein Interactions for EIF4EBP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF4E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NFYA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RDH12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF4EBP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EIF4EBP IPR008606 0.1


Protein complexes (CORUM database) featuring EIF4EBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EIF4EBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006412 translation Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0008190 eukaryotic initiation factor 4E binding Database 0.03
Category members GO Category GO:0019933 cAMP-mediated signaling Database 0
Category members GO Category GO:0045947 negative regulation of translational initiation Database 0


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