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Query: EDEM2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EDEM2 0 -0.471 -0.410 0.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EDEM2 Ubiquitylation K509 -0.471 _EFYSLK(gl)R_
EDEM2 Ubiquitylation K389 -0.847 _SLPLLLK(gl)_

Background Information for EDEM2:


Pubmed-EDEM2 »
Uniprot-EDEM2 »
Biogrid-EDEM2 »
ProteomicsDB-EDEM2 »

Tumorportal-EDEM2 »
COSMIC-EDEM2 »
GenomeRNAi-EDEM2 »
Genecards-EDEM2


Protein-protein Interactions for EDEM2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANGPTL7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C8G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHST8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYTIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDEM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM5B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBLN7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR114 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEPACAM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MXD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAAA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EDEM2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_hydro_47 IPR001382 0.04


Protein complexes (CORUM database) featuring EDEM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EDEM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0006986 response to unfolded protein Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Database 0.06
Category members Pathway Pathway_464 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE 0 0
Category members Pathway Pathway_465 REACTOME_CALNEXIN_CALRETICULIN_CYCLE 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0005788 endoplasmic reticulum lumen Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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