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Query: EDC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EDC3 0 2.440 -0.320 1.230

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EDC3 Phosphorylation S161 0.603 0.607 _HNS(ph)WSSSSR_
EDC3 Phosphorylation S131 0.233 0.276 _SQDVAVS(ph)PQQQQCSK_

Background Information for EDC3:


Pubmed-EDC3 »
Uniprot-EDC3 »
Biogrid-EDC3 »
ProteomicsDB-EDC3 »

Tumorportal-EDC3 »
COSMIC-EDC3 »
GenomeRNAi-EDC3 »
Genecards-EDC3


Protein-protein Interactions for EDC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait CRKL Cat. description Hein, Mann, Cell 2015
Category members IP bait DCP1A Cat. description Hein, Mann, Cell 2015
Category members IP bait EDC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1R35 Cat. description Hein, Mann, Cell 2015
Category members IP bait CARD9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EDC3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FDF_dom IPR019050 0.22
Category members YjeF_N_dom IPR004443 0


Protein complexes (CORUM database) featuring EDC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 559 Decapping complex Database 0.05


Categories featuring EDC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members Pathway Pathway_310 KEGG_RNA_DEGRADATION 0 0.26
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay Database 0.21
Category members GO Category GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Database 0.17
Category members Pathway Pathway_842 REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY 0 0.1
Category members GO Category GO:0000932 cytoplasmic mRNA processing body Database 0.08
Category members Pathway Pathway_843 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE 0 0


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