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Query: DSC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DSC3 0 -6.974 1.100 -0.870 -4.398 -2.576

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for DSC3:


Pubmed-DSC3 »
Uniprot-DSC3 »
Biogrid-DSC3 »
ProteomicsDB-DSC3 »

Tumorportal-DSC3 »
COSMIC-DSC3 »
GenomeRNAi-DSC3 »
Genecards-DSC3


Protein-protein Interactions for DSC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DSC3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cadherin/Desmocollin IPR009124 1.19
Category members Cadherin_pro_dom IPR014868 0.78
Category members Cadherin IPR002126 0.32
Category members Cadherin_cytoplasmic-dom IPR000233 0.29
Category members Desmosomal_cadherin IPR009122 0.28
Category members Cadherin-like IPR015919 0.21


Protein complexes (CORUM database) featuring DSC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DSC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007156 homophilic cell adhesion Database 0.28
Category members GO Category GO:0030057 desmosome Database 0.26
Category members GO Category GO:0045295 gamma-catenin binding Database 0.23
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members GO Category GO:0007155 cell adhesion Database 0


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