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Query: DOCK7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DOCK7 0 4.053 -0.180 1.240 -1.046 0.305 0.146

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DOCK7 Phosphorylation S452 1.041 1.249 _TTS(ph)GDDACNLTSFR_
DOCK7 Phosphorylation S1383 1.049 1.056 _MNS(ph)LTFK_
DOCK7 Phosphorylation S888 0.502 0.610 _SAVRPAS(ph)LNLNR_
DOCK7 Phosphorylation S2129 0.410 _AVLPVTCHRDS(ph)FSR_
DOCK7 Phosphorylation S180 0.319 0.371 _S(ph)MSIDDTPR_
DOCK7 Phosphorylation S946 0.288 _AAPWGSNPS(ph)PSAESTQAMDR_
DOCK7 Phosphorylation S929 0.481 0.241 _SNS(ph)WVNTGGPK_
DOCK7 Phosphorylation S1432 0.204 0.208 _SPS(ph)GSAFGSQENLR_
DOCK7 Ubiquitylation K381 0.138 _LK(gl)SQADQFCQR_
DOCK7 Phosphorylation S1438 -0.052 -0.235 _SPSGSAFGS(ph)QENLR_
DOCK7 Phosphorylation S898 -2.241 -0.434 _SLS(ph)NSNPDISGTPTSPDDEVR_
DOCK7 Phosphorylation T907 -0.613 -0.434 _SLS(ph)NSNPDISGT(ph)PTSPDDEVR_
DOCK7 Phosphorylation S910 -0.268 -0.548 _SLS(ph)NSNPDISGTPTS(ph)PDDEVR_
DOCK7 Phosphorylation S896 -0.852 _S(ph)LSNSNPDISGTPTSPDDEVR_
DOCK7 Phosphorylation S900 -0.947 -3.303 _SLSNS(ph)NPDISGT(ph)PTSPDDEVR_
DOCK7 Ubiquitylation K2080 0.971 _NK(gl)SLIGPDQKEYQR_
DOCK7 Ubiquitylation K2088 0.652 _SLIGPDQK(gl)EYQR_

Background Information for DOCK7:


Pubmed-DOCK7 »
Uniprot-DOCK7 »
Biogrid-DOCK7 »
ProteomicsDB-DOCK7 »

Tumorportal-DOCK7 »
COSMIC-DOCK7 »
GenomeRNAi-DOCK7 »
Genecards-DOCK7


Protein-protein Interactions for DOCK7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait NRIP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARPC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AVIL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IRF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRCH3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MOBKL1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIH1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPSAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DOCK7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members DOCK_C IPR010703 0
Category members DOCK_C/D_N IPR021816 0


Protein complexes (CORUM database) featuring DOCK7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DOCK7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0030424 axon Database 0.23
Category members Pathway Pathway_532 PID_ERBB2_ERBB3_PATHWAY 0 0.13
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0048365 Rac GTPase binding Database 0.1
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0033138 positive regulation of peptidyl-serine phosphorylation Database 0.03
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0032863 activation of Rac GTPase activity Database 0
Category members GO Category GO:0043473 pigmentation Database 0
Category members GO Category GO:0045178 basal part of cell Database 0
Category members GO Category GO:0045200 establishment of neuroblast polarity Database 0


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