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Query: DMPK

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DMPK 0 4.533 -0.990 1.550 0.369 0.295

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DMPK Phosphorylation S1721 1.103 1.216 _SLS(ph)LESTDR_
DMPK Phosphorylation S1629 0.643 0.973 _SMS(ph)ASSGLSAR_
DMPK Phosphorylation S1651 0.478 0.828 _EFS(ph)GGSYSAK_
DMPK Phosphorylation S1545 0.686 _RYS(ph)FRVPEEER_

Background Information for DMPK:


Pubmed-DMPK »
Uniprot-DMPK »
Biogrid-DMPK »
ProteomicsDB-DMPK »

Tumorportal-DMPK »
COSMIC-DMPK »
GenomeRNAi-DMPK »
Genecards-DMPK


Protein-protein Interactions for DMPK
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in DMPK
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members AGC-kinase_C IPR000961 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Myotonic_dystrophy_kinase_coil IPR014930 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring DMPK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DMPK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0031072 heat shock protein binding Database 1.59
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0006998 nuclear envelope organization Database 0.4
Category members GO Category GO:0031307 integral to mitochondrial outer membrane Database 0.24
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0005640 nuclear outer membrane Database 0.18
Category members GO Category GO:0008016 regulation of heart contraction Database 0.04
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Disease phenotype MYOTONIC_DYSTROPHY_1 MYOTONIC DYSTROPHY 1 Database 0
Category members GO Category GO:0002028 regulation of sodium ion transport Database 0
Category members GO Category GO:0006874 cellular calcium ion homeostasis Database 0
Category members GO Category GO:0010830 regulation of myotube differentiation Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0033017 sarcoplasmic reticulum membrane Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051823 regulation of synapse structural plasticity Database 0


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