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Query: DHRS4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHRS4 0 -1.439 0.180 -0.130 -1.439
DHRS4 0 -1.439 0.450 -0.560 -1.439

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for DHRS4:





Protein-protein Interactions for DHRS4

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACADVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ALDH1B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP5D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BIRC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1QTNF9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP2B6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHRS4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM60A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LMO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAUR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRDX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRELP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QPCT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHRS4

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DH_sc/Rdtase_SDR IPR002198 0
Category members Glc/ribitol_DH IPR002347 0
Category members ADH_insect IPR002424 0
Category members DHB_DH IPR003560 0
Category members PKS_KR IPR013968 0


Protein complexes (CORUM database) featuring DHRS4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHRS4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051262 protein tetramerization Database 0.6
Category members GO Category GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor Database 0.09
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Pathway Pathway_87 KEGG_RETINOL_METABOLISM 0 0
Category members GO Category GO:0000253 3-keto sterol reductase activity Database 0
Category members GO Category GO:0004090 carbonyl reductase (NADPH) activity Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006066 alcohol metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008202 steroid metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0042180 cellular ketone metabolic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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