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Query: DDX39A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX39A 0 3.247 -0.780 0.900
DDX39A 0 3.247 -0.780 0.900 0.154 -0.871 -0.414 -0.071 0.085

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX39A Phosphorylation S226 1.288 0.791 _NRS(ph)FSLK_
DDX39A Ubiquitylation K230 0.720 0.666 _SFSLK(gl)NVK_
DDX39A Phosphorylation T214 0.055 -0.353 _NCPHVVVGT(ph)PGR_
DDX39A Phosphorylation S68 -0.291 -0.639 _(ac)AEQDVENDLLDYDEEEEPQAPQES(ph)TPAPPKK_
DDX39A Phosphorylation T69 -0.639 _(ac)AEQDVENDLLDYDEEEEPQAPQES(ph)TPAPPKK_
DDX39A Phosphorylation Y56 -1.836 -1.799 _AEQDVENDLLDY(ph)DEEEEPQAPQESTPAPPK_
DDX39A Ubiquitylation K78 0.624 _DIK(gl)GSYVSIHSSGFR_
DDX39A Ubiquitylation K205 -0.507 _K(gl)NCPHVVVGTPGR_

Background Information for DDX39A:





Protein-protein Interactions for DDX39A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DDX39A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TM2D3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX39A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members Helicase/UvrB_dom IPR006935 0.78
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members RNA_helicase_DEAD_Q_motif IPR014014 0.24


Protein complexes (CORUM database) featuring DDX39A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5615 Emerin complex 52 Database 0.99


Categories featuring DDX39A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0016787 hydrolase activity Database 0.22


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