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Query: DDOST

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDOST 0 0.156 1.280 -0.390 0.151 -0.462 0.509 0.295

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDOST Ubiquitylation K189 -0.337 _APTIVGK(gl)SSLNPILFR_

Background Information for DDOST:


Pubmed-DDOST »
Uniprot-DDOST »
Biogrid-DDOST »
ProteomicsDB-DDOST »

Tumorportal-DDOST »
COSMIC-DDOST »
GenomeRNAi-DDOST »
Genecards-DDOST


Protein-protein Interactions for DDOST
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FANCI Cat. description Hein, Mann, Cell 2015
Category members IP bait IGBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAEP Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6C Cat. description Hein, Mann, Cell 2015
Category members IP bait SACM1L Cat. description Hein, Mann, Cell 2015
Category members IP bait VIM Cat. description Hein, Mann, Cell 2015
Category members IP bait RPN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDOST
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring DDOST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1199 Oligosaccharyltransferase complex (Stt3A variant) Database 0.78
Category members Corum 1200 Oligosaccharyltransferase complex (Stt3B variant) Database 0.78


Categories featuring DDOST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0004576 oligosaccharyl transferase activity Database 0.53
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity Database 0.38
Category members GO Category GO:0008250 oligosaccharyltransferase complex Database 0.33
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0006486 protein glycosylation Database 0.21
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_109 KEGG_N_GLYCAN_BIOSYNTHESIS 0 0.04
Category members Pathway Pathway_457 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING 0 0.04
Category members GO Category GO:0042110 T cell activation Database 0.02
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0006487 protein N-linked glycosylation Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0034097 response to cytokine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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