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Query: CYB5R3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CYB5R3 0 1.601 0.070 -0.120 0.487 0.294 0.404

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CYB5R3 Ubiquitylation K163 0.544 -0.128 _FAIRPDK(gl)K_
CYB5R3 Ubiquitylation K115 -0.445 -0.904 _VYFK(gl)DTHPK_
CYB5R3 Ubiquitylation K42 -1.893 -1.012 _STPAITLESPDIK(gl)YPLR_
CYB5R3 Ubiquitylation K164 -0.539 -1.580 _K(gl)SNPIIR_
CYB5R3 Ubiquitylation K120 -1.238 _DTHPK(gl)FPAGGK_

Background Information for CYB5R3:


Pubmed-CYB5R3 »
Uniprot-CYB5R3 »
Biogrid-CYB5R3 »
ProteomicsDB-CYB5R3 »

Tumorportal-CYB5R3 »
COSMIC-CYB5R3 »
GenomeRNAi-CYB5R3 »
Genecards-CYB5R3


Protein-protein Interactions for CYB5R3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTL6A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AMTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC37A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPAN11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CYB5R3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NADH-Cyt_B5_reductase IPR001834 0.06
Category members OxRdtase_FAD/NAD-bd IPR001433 0
Category members Flavoprot_Pyr_Nucl_cyt_Rdtase IPR001709 0
Category members OxRdtase_FAD-bd_dom IPR008333 0
Category members Riboflavin_synthase-like_b-brl IPR017938 0


Protein complexes (CORUM database) featuring CYB5R3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CYB5R3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0051287 NAD binding Database 1.6
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members GO Category GO:0016208 AMP binding Database 0.2
Category members Pathway Pathway_279 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS 0 0.18
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0050660 flavin adenine dinucleotide binding Database 0.12
Category members GO Category GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H Database 0.08
Category members Pathway Pathway_61 KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 0 0.04
Category members GO Category GO:0019852 L-ascorbic acid metabolic process Database 0.04
Category members GO Category GO:0005811 lipid particle Database 0
Category members GO Category GO:0005833 hemoglobin complex Database 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0008015 blood circulation Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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