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Query: CTNND1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTNND1 0 5.998 -0.610 1.090
CTNND1 0 5.998 -0.610 1.090 0.656 0.248 0.133 0.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CTNND1 Ubiquitylation K25 0.530 0.979 _EQEAQFEK(gl)LTR_
CTNND1 Phosphorylation Y865 0.634 0.963 _SQSSHSY(ph)DDSTLPLIDR_
CTNND1 Phosphorylation S349 1.049 0.905 _GSLAS(ph)LDSLRK_
CTNND1 Phosphorylation S899 0.562 _S(ph)GDLGDMEPLK_
CTNND1 Phosphorylation S864 0.521 _SQSSHS(ph)YDDSTLPLIDR_
CTNND1 Phosphorylation S288 1.010 0.270 _S(ph)M(ox)GYDDLDYGM(ox)M(ox)SDYGTAR_
CTNND1 Phosphorylation S252 -0.119 0.039 _APS(ph)RQDVYGPQPQVR_
CTNND1 Ubiquitylation K355 -1.397 -0.159 _K(gl)GGPPPPNWR_
CTNND1 Phosphorylation S268 -0.368 _VGGS(ph)SVDLHR_
CTNND1 Ubiquitylation K909 -0.895 -0.440 _SGDLGDMEPLK(gl)GTTPLMQK_
CTNND1 Ubiquitylation K633 -1.794 _GK(gl)KPIEDPANDTVDFPKR_
CTNND1 Ubiquitylation K676 -0.804 _ESK(gl)TPAILEASAGAIQNLCAGR_

Background Information for CTNND1:


Pubmed-CTNND1 »
Uniprot-CTNND1 »
Biogrid-CTNND1 »
ProteomicsDB-CTNND1 »

Tumorportal-CTNND1 »
COSMIC-CTNND1 »
GenomeRNAi-CTNND1 »
Genecards-CTNND1


Protein-protein Interactions for CTNND1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTNNA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CTNND1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Armadillo IPR000225 1.58


Protein complexes (CORUM database) featuring CTNND1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CTNND1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0030426 growth cone Database 1.61
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members Pathway Pathway_611 PID_ECADHERIN_KERATINOCYTE_PATHWAY 0 1.34
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005913 cell-cell adherens junction Database 1.05
Category members GO Category GO:0005915 zonula adherens Database 0.93
Category members Pathway Pathway_295 PID_ARF6_TRAFFICKING_PATHWAY 0 0.9
Category members GO Category GO:0043197 dendritic spine Database 0.86
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0019903 protein phosphatase binding Database 0.33
Category members Pathway Pathway_562 PID_NCADHERIN_PATHWAY 0 0.29
Category members GO Category GO:0034329 cell junction assembly Database 0.29
Category members GO Category GO:0045296 cadherin binding Database 0.26
Category members Pathway Pathway_560 REACTOME_CELL_CELL_COMMUNICATION 0 0.25
Category members Pathway Pathway_605 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 0 0.2
Category members Pathway Pathway_294 PID_AJDISS_2PATHWAY 0 0.18
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0045216 cell-cell junction organization Database 0.1
Category members GO Category GO:0001738 morphogenesis of a polarized epithelium Database 0.09
Category members GO Category GO:0045202 synapse Database 0.06
Category members Pathway Pathway_1237 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION 0 0
Category members Pathway Pathway_1276 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS 0 0
Category members Pathway Pathway_657 PID_FGF_PATHWAY 0 0
Category members Pathway Pathway_925 REACTOME_CELL_JUNCTION_ORGANIZATION 0 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0007435 salivary gland morphogenesis Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0034332 adherens junction organization Database 0
Category members GO Category GO:0050839 cell adhesion molecule binding Database 0


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