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Query: COPB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
COPB2 0 0.012 0.442 0.456 0.355 -0.100 -0.317

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
COPB2 Phosphorylation T861 -0.735 -0.376 _STAQQELDGKPASPT(ph)PVIVASHTANKEEK_
COPB2 Phosphorylation S859 -0.448 -0.489 _STAQQELDGKPAS(ph)PTPVIVASHTANKEEK_

Background Information for COPB2:


Pubmed-COPB2 »
Uniprot-COPB2 »
Biogrid-COPB2 »
ProteomicsDB-COPB2 »

Tumorportal-COPB2 »
COSMIC-COPB2 »
GenomeRNAi-COPB2 »
Genecards-COPB2


Protein-protein Interactions for COPB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COPA Cat. description Hein, Mann, Cell 2015
Category members IP bait SACM1L Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP5D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in COPB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12
Category members Coatomer_WD-assoc_reg IPR006692 0


Protein complexes (CORUM database) featuring COPB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5230 CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex Database 0


Categories featuring COPB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0006891 intra-Golgi vesicle-mediated transport Database 0.1
Category members GO Category GO:0006890 retrograde vesicle-mediated transport, Golgi to ER Database 0.05
Category members Pathway Pathway_1272 REACTOME_COPI_MEDIATED_TRANSPORT 0 0
Category members GO Category GO:0030117 membrane coat Database 0
Category members GO Category GO:0030126 COPI vesicle coat Database 0
Category members GO Category GO:0048205 COPI coating of Golgi vesicle Database 0


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