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Query: CNOT10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CNOT10 0 -1.303 0.550 -0.140
CNOT10 0 -1.303 0.550 -0.140 -0.512 0.364

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CNOT10 Ubiquitylation K472 -1.155 _GTSEQETK(gl)GLPSKK_

Background Information for CNOT10:


Pubmed-CNOT10 »
Uniprot-CNOT10 »
Biogrid-CNOT10 »
ProteomicsDB-CNOT10 »

Tumorportal-CNOT10 »
COSMIC-CNOT10 »
GenomeRNAi-CNOT10 »
Genecards-CNOT10


Protein-protein Interactions for CNOT10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait C2orf29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPZA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNOT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CXorf48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GADD45B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MMP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NANOS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIBC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX13A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CNOT10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR_repeat IPR019734 0.93


Protein complexes (CORUM database) featuring CNOT10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CNOT10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_310 KEGG_RNA_DEGRADATION 0 0.26
Category members GO Category GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Database 0.17
Category members Pathway Pathway_842 REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY 0 0.1
Category members GO Category GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening Database 0.06
Category members Pathway Pathway_841 REACTOME_DEADENYLATION_OF_MRNA 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0030014 CCR4-NOT complex Database 0
Category members GO Category GO:0031047 gene silencing by RNA Database 0


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