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Query: CLK3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CLK3 0 1.466 0.000 0.270
CLK3 0 1.466 0.000 0.270 1.140 0.556 0.830

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CLK3 Phosphorylation Y163 -0.111 _YRSPEPDPY(ph)LSYR_
CLK3 Phosphorylation S157 -0.522 -0.435 _S(ph)PEPDPYLSYR_
CLK3 Ubiquitylation K328 -0.697 _GK(gl)SQVALK_
CLK3 Ubiquitylation K460 -1.413 _SVK(gl)NTSIR_

Background Information for CLK3:


Pubmed-CLK3 »
Uniprot-CLK3 »
Biogrid-CLK3 »
ProteomicsDB-CLK3 »

Tumorportal-CLK3 »
COSMIC-CLK3 »
GenomeRNAi-CLK3 »
Genecards-CLK3


Protein-protein Interactions for CLK3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MTX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ORMDL1;ORMDL2;ORMDL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAH Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB48 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait U2AF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CLK3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CLK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CLK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0001669 acrosomal vesicle Database 0
Category members GO Category GO:0004712 protein serine/threonine/tyrosine kinase activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0018108 peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0043484 regulation of RNA splicing Database 0


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