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Query: CIRBP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CIRBP 0 0.840 -0.810 0.840 0.581 -0.442

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CIRBP:





Protein-protein Interactions for CIRBP

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NRIP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ORC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPOLA Cat. description Hein, Mann, Cell 2015
Category members IP bait PLK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD54L Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRAPPC8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CIRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CIRBP

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members RRM_dom_euk IPR003954 0.18


Protein complexes (CORUM database) featuring CIRBP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring CIRBP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0009411 response to UV Database 0.79
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0003730 mRNA 3'-UTR binding Database 0.24
Category members GO Category GO:0030371 translation repressor activity Database 0.2
Category members GO Category GO:0034063 stress granule assembly Database 0.13
Category members GO Category GO:0009409 response to cold Database 0
Category members GO Category GO:0045727 positive regulation of translation Database 0
Category members GO Category GO:0048255 mRNA stabilization Database 0


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