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Query: CGN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CGN 0 3.181 -0.850 0.720 0.110 0.304

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CGN Phosphorylation S155 0.173 0.694 _SNS(ph)MLELAPK_
CGN Ubiquitylation K356 0.623 0.473 _MQPLVMVSSGSTK(gl)AVAGQGELTR_
CGN Phosphorylation S165 0.257 0.197 _VAS(ph)PGSTIDTAPLSSVDSLINK_
CGN Phosphorylation S137 0.172 -0.057 _SHS(ph)QASLAGPGPVDPSNR_
CGN Ubiquitylation K505 -0.299 -0.432 _GALK(gl)EEVASR_
CGN Phosphorylation S140 -0.337 _SHSQAS(ph)LAGPGPVDPSNR_
CGN Phosphorylation S168 -0.012 _VASPGS(ph)TIDTAPLSSVDSLINK_
CGN Ubiquitylation K483 -0.071 _ELLEEVLEGK(gl)QR_
CGN Ubiquitylation K965 -0.723 _QLK(gl)GLEEK_

Background Information for CGN:


Pubmed-CGN »
Uniprot-CGN »
Biogrid-CGN »
ProteomicsDB-CGN »

Tumorportal-CGN »
COSMIC-CGN »
GenomeRNAi-CGN »
Genecards-CGN


Protein-protein Interactions for CGN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CGN Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH11 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DAB2IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CGN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Myosin_tail IPR002928 0


Protein complexes (CORUM database) featuring CGN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CGN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members Pathway Pathway_777 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 0 0.89
Category members Pathway Pathway_792 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION 0 0.75
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0043296 apical junction complex Database 0.18
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0030054 cell junction Database 0


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