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Query: CDC34

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDC34 1 2.102 -0.790 0.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDC34 Ubiquitylation K157 1.502 _GK(gl)DREYTDIIR_

Background Information for CDC34:


Pubmed-CDC34 »
Uniprot-CDC34 »
Biogrid-CDC34 »
ProteomicsDB-CDC34 »

Tumorportal-CDC34 »
COSMIC-CDC34 »
GenomeRNAi-CDC34 »
Genecards-CDC34


Protein-protein Interactions for CDC34
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BTRC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEANC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDC34
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring CDC34
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2170 Ubiquitin E3 ligase (CDC34, CUL1, RBX1) Database 0


Categories featuring CDC34
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0006270 DNA replication initiation Database 0.57
Category members Pathway Pathway_982 BIOCARTA_G2_PATHWAY 0 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0043951 negative regulation of cAMP-mediated signaling Database 0.08
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members Pathway Pathway_1250 BIOCARTA_SKP2E2F_PATHWAY 0 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0043525 positive regulation of neuron apoptotic process Database 0
Category members GO Category GO:0070848 response to growth factor Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0


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