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Query: CD276

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CD276 2 3.135 0.360 -0.520
CD276 2 3.135 0.360 -0.520 -0.095 0.178

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CD276 Phosphorylation S525 1.617 1.750 _HSDS(ph)KEDDGQEIA_
CD276 Ubiquitylation K521 -0.204 -0.111 _TALQPLK(gl)HSDSK_
CD276 Ubiquitylation K526 -0.204 -0.111 _TALQPLK(gl)HSDSKEDDGQEIA_

Background Information for CD276:


Pubmed-CD276 »
Uniprot-CD276 »
Biogrid-CD276 »
ProteomicsDB-CD276 »

Tumorportal-CD276 »
COSMIC-CD276 »
GenomeRNAi-CD276 »
Genecards-CD276


Protein-protein Interactions for CD276
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CEACAM21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LILRB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNF Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CD276
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Ig_V-set IPR013106 0.09
Category members Ig_V-set_subgr IPR003596 0
Category members Ig_C1-set IPR003597 0
Category members CD80_C2-set IPR013162 0


Protein complexes (CORUM database) featuring CD276
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CD276
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0042102 positive regulation of T cell proliferation Database 0.04
Category members GO Category GO:0042110 T cell activation Database 0.02
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0030501 positive regulation of bone mineralization Database 0
Category members GO Category GO:0042130 negative regulation of T cell proliferation Database 0
Category members GO Category GO:0045077 negative regulation of interferon-gamma biosynthetic process Database 0
Category members GO Category GO:0045078 positive regulation of interferon-gamma biosynthetic process Database 0
Category members GO Category GO:0045085 negative regulation of interleukin-2 biosynthetic process Database 0
Category members GO Category GO:0045669 positive regulation of osteoblast differentiation Database 0
Category members GO Category GO:0050728 negative regulation of inflammatory response Database 0
Category members GO Category GO:0050776 regulation of immune response Database 0


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