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Query: CASP14

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CASP14 0 -4.487 0.690 0.120 -4.487

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CASP14:


Pubmed-CASP14 »
Uniprot-CASP14 »
Biogrid-CASP14 »
ProteomicsDB-CASP14 »

Tumorportal-CASP14 »
COSMIC-CASP14 »
GenomeRNAi-CASP14 »
Genecards-CASP14


Protein-protein Interactions for CASP14
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FTH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZIC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CASP14
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Pept_C14_ICE_p20 IPR001309 0.07
Category members Pept_C14_caspase IPR011600 0.07
Category members Pept_C14A_p45_core IPR015917 0.04
Category members Pept_C14_p10 IPR002138 0


Protein complexes (CORUM database) featuring CASP14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CASP14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0045095 keratin filament Database 0.35
Category members GO Category GO:0031424 keratinization Database 0.04
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0008544 epidermis development Database 0


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