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Query: CAPZB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAPZB 1 3.365 0.940 -1.150 0.175 0.103 0.384 0.305 -0.428

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CAPZB Ubiquitylation K315 1.983 _SVQTFADK(gl)SK_
CAPZB Ubiquitylation K317 0.515 1.983 _SVQTFADKSK(gl)_
CAPZB Ubiquitylation K300 0.315 1.544 _STLNEIYFGKTK(gl)_
CAPZB Ubiquitylation K298 0.345 1.035 _STLNEIYFGK(gl)TK_
CAPZB Ubiquitylation K286 0.843 0.715 _LVEDMENK(gl)IR_

Background Information for CAPZB:


Pubmed-CAPZB »
Uniprot-CAPZB »
Biogrid-CAPZB »
ProteomicsDB-CAPZB »

Tumorportal-CAPZB »
COSMIC-CAPZB »
GenomeRNAi-CAPZB »
Genecards-CAPZB


Protein-protein Interactions for CAPZB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN4 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MARK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH11 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CC Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS1BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VCL Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS26A Cat. description Hein, Mann, Cell 2015
Category members IP bait WASH3P Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPZA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SH3KBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAPZB
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CAPZB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 846 RICH1/AMOT polarity complex, Flag-Rich1 precipitated Database 0


Categories featuring CAPZB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0008290 F-actin capping protein complex Database 1.36
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0030032 lamellipodium assembly Database 0.66
Category members GO Category GO:0014704 intercalated disc Database 0.64
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0030018 Z disc Database 0.32
Category members GO Category GO:0071203 WASH complex Database 0.31
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0030863 cortical cytoskeleton Database 0.24
Category members GO Category GO:0051016 barbed-end actin filament capping Database 0.21
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0048487 beta-tubulin binding Database 0.1
Category members GO Category GO:0031115 negative regulation of microtubule polymerization Database 0.08
Category members GO Category GO:0001669 acrosomal vesicle Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0022604 regulation of cell morphogenesis Database 0
Category members GO Category GO:0030030 cell projection organization Database 0
Category members GO Category GO:0048747 muscle fiber development Database 0


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