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Query: CACYBP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CACYBP 2 11.842 0.480 -0.310 1.995 0.414 0.588 0.866 -0.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CACYBP Phosphorylation S3 1.210 1.073 _(ac)AS(ph)EELQKDLEEVK_
CACYBP Ubiquitylation K212 0.244 0.832 _TINK(gl)AWVESR_
CACYBP Ubiquitylation K19 0.761 0.125 _VLLEK(gl)ATR_
CACYBP Ubiquitylation K146 0.061 -0.044 _VK(gl)TDTVLILCR_
CACYBP Ubiquitylation K196 -0.454 _EKPSYDTETDPSEGLMNVLK(gl)K_
CACYBP Ubiquitylation K197 -0.454 _EKPSYDTETDPSEGLMNVLK(gl)K_
CACYBP Ubiquitylation K33 5.154 _VRDALTAEK(gl)SK_
CACYBP Ubiquitylation K41 0.333 _SKIETEIK(gl)NK_
CACYBP Ubiquitylation K43 0.550 _SKIETEIK(gl)NK_
CACYBP Ubiquitylation K51 -0.494 _K(gl)AELLDNEKPAAVVAPITTGYTVK_
CACYBP Ubiquitylation K207 0.581 _IYEDGDDDMK(gl)R_
CACYBP Ubiquitylation K223 0.413 _EKQAK(gl)GDTEF_

Background Information for CACYBP:


Pubmed-CACYBP »
Uniprot-CACYBP »
Biogrid-CACYBP »
ProteomicsDB-CACYBP »

Tumorportal-CACYBP »
COSMIC-CACYBP »
GenomeRNAi-CACYBP »
Genecards-CACYBP


Protein-protein Interactions for CACYBP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SNX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CACYBP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CS_dom IPR007052 0.57
Category members SGS IPR007699 0.29
Category members HSP20-like_chaperone IPR008978 0.18


Protein complexes (CORUM database) featuring CACYBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1255 Ubiquitin E3 ligase (SIAH1, SIP, SKP1A, TBL1X) Database 0.1


Categories featuring CACYBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030877 beta-catenin destruction complex Database 0.31
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0005641 nuclear envelope lumen Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0044297 cell body Database 0
Category members GO Category GO:0045740 positive regulation of DNA replication Database 0
Category members GO Category GO:0055007 cardiac muscle cell differentiation Database 0
Category members GO Category GO:0060416 response to growth hormone Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0
Category members GO Category GO:0071277 cellular response to calcium ion Database 0


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