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Query: BTG1

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BTG1 0 0.279

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BTG1 Ubiquitylation K150 0.279 _ISCK(gl)EELLLGR_

Background Information for BTG1:


Pubmed-BTG1 »
Uniprot-BTG1 »
Biogrid-BTG1 »
ProteomicsDB-BTG1 »

Tumorportal-BTG1 »
COSMIC-BTG1 »
GenomeRNAi-BTG1 »
Genecards-BTG1


Protein-protein Interactions for BTG1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in BTG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Anti_prolifrtn IPR002087 0.09


Protein complexes (CORUM database) featuring BTG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BTG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0003712 transcription cofactor activity Database 0.21
Category members GO Category GO:0045766 positive regulation of angiogenesis Database 0.19
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0045603 positive regulation of endothelial cell differentiation Database 0
Category members GO Category GO:0045663 positive regulation of myoblast differentiation Database 0


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