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Query: BRF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BRF1 0 2.966 -0.990 1.780

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BRF1 Phosphorylation T365 0.704 0.482 _DGSTEDTASSLCGEEDT(ph)EDEELEAAASHLNK_
BRF1 Phosphorylation S553 0.355 0.122 _GLSSAGGGS(ph)PHREDAQPEHSASAR_
BRF1 Phosphorylation S450 -0.470 _DASGDGELDLS(ph)GIDDLEIDR_

Background Information for BRF1:


Pubmed-BRF1 »
Uniprot-BRF1 »
Biogrid-BRF1 »
ProteomicsDB-BRF1 »

Tumorportal-BRF1 »
COSMIC-BRF1 »
GenomeRNAi-BRF1 »
Genecards-BRF1


Protein-protein Interactions for BRF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACSL4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC132 Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GPSM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR3E Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait TBP;TBPL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCF20 Cat. description Hein, Mann, Cell 2015
Category members IP bait VBP1 Cat. description Hein, Mann, Cell 2015


Protein Domains in BRF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TFIIB IPR000812 0
Category members Cyclin_N IPR006671 0
Category members Znf_TFIIB IPR013137 0
Category members TFIIB_cyclin IPR013150 0
Category members Cyclin-like IPR013763 0


Protein complexes (CORUM database) featuring BRF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1114 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex Database 0.25


Categories featuring BRF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0006352 DNA-dependent transcription, initiation Database 3.76
Category members Pathway Pathway_355 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER 0 0.37
Category members GO Category GO:0017025 TBP-class protein binding Database 0.35
Category members Pathway Pathway_357 REACTOME_RNA_POL_III_TRANSCRIPTION 0 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006383 transcription from RNA polymerase III promoter Database 0.18
Category members GO Category GO:0009304 tRNA transcription Database 0.18
Category members GO Category GO:0043488 regulation of mRNA stability Database 0.07
Category members GO Category GO:0006384 transcription initiation from RNA polymerase III promoter Database 0.01
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0009303 rRNA transcription Database 0


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