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Query: BRD7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BRD7 0 3.645 0.610 -0.560 0.433 0.833 0.498

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BRD7 Phosphorylation S279 0.963 0.918 _EREDS(ph)GDAEAHAFK_
BRD7 Phosphorylation S621 -0.540 _AM(ox)GISIPS(ph)PVMENNFVDLTEDTEEPK_

Background Information for BRD7:


Pubmed-BRD7 »
Uniprot-BRD7 »
Biogrid-BRD7 »
ProteomicsDB-BRD7 »

Tumorportal-BRD7 »
COSMIC-BRD7 »
GenomeRNAi-BRD7 »
Genecards-BRD7


Protein-protein Interactions for BRD7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait REEP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMARCC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMARCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMARCE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BRD7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members DUF3512 IPR021900 0


Protein complexes (CORUM database) featuring BRD7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BRD7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0070577 histone acetyl-lysine binding Database 0.88
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0035066 positive regulation of histone acetylation Database 0


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