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Query: BECN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BECN1 0 0.066 0.080 -0.010

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BECN1 Ubiquitylation K324 0.066 _MGLK(gl)FQR_
BECN1 Ubiquitylation K237 -0.057 _EYSEFK(gl)R_

Background Information for BECN1:


Pubmed-BECN1 »
Uniprot-BECN1 »
Biogrid-BECN1 »
ProteomicsDB-BECN1 »

Tumorportal-BECN1 »
COSMIC-BECN1 »
GenomeRNAi-BECN1 »
Genecards-BECN1


Protein-protein Interactions for BECN1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BECN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FBL Cat. description Hein, Mann, Cell 2015
Category members IP bait NLRP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NLRP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT11 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATG14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C13orf18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRBF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BECN1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Translin IPR002848 0


Protein complexes (CORUM database) featuring BECN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BECN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0016239 positive regulation of macroautophagy Database 0.09
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members Pathway Pathway_526 KEGG_REGULATION_OF_AUTOPHAGY 0 0
Category members GO Category GO:0000045 autophagic vacuole assembly Database 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0006968 cellular defense response Database 0
Category members GO Category GO:0007040 lysosome organization Database 0
Category members GO Category GO:0033197 response to vitamin E Database 0
Category members GO Category GO:0048666 neuron development Database 0
Category members GO Category GO:0050435 beta-amyloid metabolic process Database 0
Category members GO Category GO:0051707 response to other organism Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0
Category members GO Category GO:0071364 cellular response to epidermal growth factor stimulus Database 0


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