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Query: ATXN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATXN2 0 -3.238 -0.480 0.100 -1.858 -0.941 -0.424

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATXN2 Phosphorylation S784 -0.208 0.376 _GIS(ph)PVVSEHR_
ATXN2 Ubiquitylation K349 -0.862 0.369 _DMDSSYAK(gl)R_
ATXN2 Phosphorylation S669 0.002 0.244 _TSPS(ph)GGTWSSVVSGVPR_
ATXN2 Phosphorylation S667 0.034 _TS(ph)PSGGTWSSVVSGVPR_
ATXN2 Phosphorylation S772 -0.093 -0.116 _ENIKPNETS(ph)PSFSK_
ATXN2 Phosphorylation T771 -0.128 -0.274 _QNSPAGNKENIKPNET(ph)SPSFSK_
ATXN2 Phosphorylation S624 -1.157 -0.461 _MSSEGPPRMS(ph)PK_
ATXN2 Phosphorylation S889 -0.710 _RGPEVTSQGVQTSS(ph)PACK_
ATXN2 Phosphorylation S616 -0.891 _RM(ox)S(ph)SEGPPRM(ox)SPK_
ATXN2 Ubiquitylation K455 -1.801 _ANQLAEEIESSAQYK(gl)AR_

Background Information for ATXN2:


Pubmed-ATXN2 »
Uniprot-ATXN2 »
Biogrid-ATXN2 »
ProteomicsDB-ATXN2 »

Tumorportal-ATXN2 »
COSMIC-ATXN2 »
GenomeRNAi-ATXN2 »
Genecards-ATXN2


Protein-protein Interactions for ATXN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATXN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CARD8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNDBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CELA2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CELF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLASRP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ESRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM98A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBFOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ATXN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ataxin-2_C IPR009818 0.19
Category members LsmAD_domain IPR009604 0
Category members LSM_dom IPR010920 0


Protein complexes (CORUM database) featuring ATXN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ATXN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Disease phenotype Amyotrophic_lateral_sclerosis Amyotrophic lateral sclerosis Database 0.21
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0034063 stress granule assembly Database 0.13
Category members GO Category GO:0005844 polysome Database 0.09
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0033962 cytoplasmic mRNA processing body assembly Database 0.07
Category members GO Category GO:0048872 homeostasis of number of cells Database 0.05
Category members GO Category GO:0002091 negative regulation of receptor internalization Database 0
Category members GO Category GO:0005154 epidermal growth factor receptor binding Database 0
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0021702 cerebellar Purkinje cell differentiation Database 0
Category members GO Category GO:0040015 negative regulation of multicellular organism growth Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0
Category members GO Category GO:0050658 RNA transport Database 0
Category members GO Category GO:0050905 neuromuscular process Database 0


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