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Query: ASPSCR1

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ASPSCR1 0 -0.972 0.610 -1.080

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ASPSCR1 Phosphorylation S275 -0.742 -0.230 _SLSS(ph)PGGPSKPK_
ASPSCR1 Phosphorylation S500 -1.623 -1.535 _AAGS(ph)PSPLPAPDPAPK_
ASPSCR1 Phosphorylation S502 -2.061 -2.218 _AAGSPS(ph)PLPAPDPAPK_

Background Information for ASPSCR1:


Pubmed-ASPSCR1 »
Uniprot-ASPSCR1 »
Biogrid-ASPSCR1 »
ProteomicsDB-ASPSCR1 »

Tumorportal-ASPSCR1 »
COSMIC-ASPSCR1 »
GenomeRNAi-ASPSCR1 »
Genecards-ASPSCR1


Protein-protein Interactions for ASPSCR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait VCP Cat. description Hein, Mann, Cell 2015
Category members IP bait ASNA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FADS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM136A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAPDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLUL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HACL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HPD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCTD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAT1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSFL1C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SHKBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBXN2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBXN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBXN6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VCP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ASPSCR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members UBX_dom IPR001012 0.08


Protein complexes (CORUM database) featuring ASPSCR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ASPSCR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0042593 glucose homeostasis Database 0.18
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0012506 vesicle membrane Database 0.01
Category members Disease phenotype Translocation_renal_cell_carcinoma Translocation renal cell carcinoma Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0009898 cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0012505 endomembrane system Database 0
Category members GO Category GO:0019898 extrinsic to membrane Database 0
Category members GO Category GO:0046324 regulation of glucose import Database 0


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