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Query: ARL8B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARL8B 0 0.553 0.400 -0.100 0.105 0.781 -0.457

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARL8B Ubiquitylation K193 0.027 -0.061 _DLPNALDEK(gl)QLIEK_
ARL8B Ubiquitylation K114 -0.375 _KVTK(gl)GNVTIK_
ARL8B Ubiquitylation K198 0.185 _QLIEK(gl)MNLSAIQDR_

Background Information for ARL8B:


Pubmed-ARL8B »
Uniprot-ARL8B »
Biogrid-ARL8B »
ProteomicsDB-ARL8B »

Tumorportal-ARL8B »
COSMIC-ARL8B »
GenomeRNAi-ARL8B »
Genecards-ARL8B


Protein-protein Interactions for ARL8B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALPI Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf104 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPLX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGUOK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM63B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRPR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OAZ3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMEL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB7L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAET1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGOL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARL8B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members SRP_receptor_beta_su IPR019009 0.13
Category members Gprotein_alpha_su IPR001019 0.02
Category members Small_GTPase_SAR1 IPR006687 0
Category members Small_GTPase_ARF IPR024156 0


Protein complexes (CORUM database) featuring ARL8B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARL8B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0048487 beta-tubulin binding Database 0.1
Category members GO Category GO:0019001 guanyl nucleotide binding Database 0.07
Category members GO Category GO:0031683 G-protein beta/gamma-subunit complex binding Database 0.02
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0043014 alpha-tubulin binding Database 0
Category members GO Category GO:0051233 spindle midzone Database 0


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