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Query: ARL8A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARL8A 1 2.807 -1.930 3.380

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARL8A Ubiquitylation K141 -0.106 -0.468 _DLPGALDEK(gl)ELIEK_

Background Information for ARL8A:





Protein-protein Interactions for ARL8A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GNAI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LITAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARL8A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members SRP_receptor_beta_su IPR019009 0.13
Category members Gprotein_alpha_su IPR001019 0.02
Category members Small_GTPase_SAR1 IPR006687 0
Category members Small_GTPase_ARF IPR024156 0


Protein complexes (CORUM database) featuring ARL8A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARL8A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0048487 beta-tubulin binding Database 0.1
Category members GO Category GO:0019001 guanyl nucleotide binding Database 0.07
Category members GO Category GO:0031683 G-protein beta/gamma-subunit complex binding Database 0.02
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0043014 alpha-tubulin binding Database 0
Category members GO Category GO:0051233 spindle midzone Database 0


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