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Query: APPL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
APPL2 0 0.352 0.480 -0.340

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
APPL2 Ubiquitylation K226 0.352 _GAEMFSK(gl)R_

Background Information for APPL2:





Protein-protein Interactions for APPL2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APPL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in APPL2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14
Category members PTB/PI_dom IPR006020 0
Category members PTB IPR013625 0


Protein complexes (CORUM database) featuring APPL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring APPL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016581 NuRD complex Database 1.15
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0010008 endosome membrane Database 0


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