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Query: AP4M1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AP4M1 1 2.834 1.440 -1.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AP4M1 Phosphorylation S133 1.202 _LSVLIAS(ph)NGSLLK_
AP4M1 Phosphorylation S128 1.632 _LS(ph)VLIASNGSLLK_

Background Information for AP4M1:


Pubmed-AP4M1 »
Uniprot-AP4M1 »
Biogrid-AP4M1 »
ProteomicsDB-AP4M1 »

Tumorportal-AP4M1 »
COSMIC-AP4M1 »
GenomeRNAi-AP4M1 »
Genecards-AP4M1


Protein-protein Interactions for AP4M1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP4E1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP4M1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP4S1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ENTHD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SUV39H2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AP4M1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Longin-like_dom IPR011012 0.34
Category members AP_mu_sigma_su IPR022775 0.25
Category members Clathrin_mu_C IPR008968 0.02
Category members Clathrin_mu IPR001392 0
Category members MHD IPR028565 0


Protein complexes (CORUM database) featuring AP4M1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 67 AP4 adaptor complex Database 0


Categories featuring AP4M1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0006895 Golgi to endosome transport Database 0.25
Category members GO Category GO:0005905 coated pit Database 0.17
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0030131 clathrin adaptor complex Database 0.11
Category members GO Category GO:0030119 AP-type membrane coat adaptor complex Database 0.03
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members Disease phenotype Severe_intellectual_disability_and_progressive_spastic_paraplegia Severe intellectual disability and progressive spastic paraplegia Database 0
Category members GO Category GO:0000138 Golgi trans cisterna Database 0
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0006810 transport Database 0


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