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Query: AP3M2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AP3M2 0 -2.249 0.330 -0.600 -0.529 -0.213 -0.553

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AP3M2 Ubiquitylation K413 -0.636 -0.807 _AGK(gl)FQVR_
AP3M2 Ubiquitylation K283 -0.147 _HSISFK(gl)ENSSCGR_

Background Information for AP3M2:





Protein-protein Interactions for AP3M2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP3M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3M2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP3S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AP3M2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Longin-like_dom IPR011012 0.34
Category members AP_mu_sigma_su IPR022775 0.25
Category members Clathrin_mu_C IPR008968 0.02
Category members Clathrin_mu IPR001392 0
Category members MHD IPR028565 0


Protein complexes (CORUM database) featuring AP3M2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 59 AP3 adapter complex Database 0.58
Category members Corum 652 AP3-BLOC1 complex Database 0


Categories featuring AP3M2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030131 clathrin adaptor complex Database 0.11
Category members GO Category GO:0030119 AP-type membrane coat adaptor complex Database 0.03
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0008089 anterograde axon cargo transport Database 0
Category members GO Category GO:0048490 anterograde synaptic vesicle transport Database 0


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