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Query: AMFR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AMFR 0 -0.242 0.190 0.100 -0.357 -0.016

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AMFR Ubiquitylation K573 0.073 _FSK(gl)SADER_
AMFR Phosphorylation S523 0.058 _SDSIRPALNSPVERPSS(ph)DQEEGETSAQTER_

Background Information for AMFR:


Pubmed-AMFR »
Uniprot-AMFR »
Biogrid-AMFR »
ProteomicsDB-AMFR »

Tumorportal-AMFR »
COSMIC-AMFR »
GenomeRNAi-AMFR »
Genecards-AMFR


Protein-protein Interactions for AMFR
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATG9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLRA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD17B3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC13A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC17A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC45A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AMFR
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0
Category members CUE IPR003892 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring AMFR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 4977 gp78-p97/VCP-DERL1 complex Database 0.2


Categories featuring AMFR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0030433 ER-associated ubiquitin-dependent protein catabolic process Database 0.33
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0007611 learning or memory Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051259 protein oligomerization Database 0


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