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Query: AKIRIN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AKIRIN2 0 -2.033 -0.130 0.530

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AKIRIN2 Phosphorylation S21 -1.238 -1.325 _RTLDFDPLLSPAS(ph)PK_

Background Information for AKIRIN2:





Protein-protein Interactions for AKIRIN2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PSMB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB5 Cat. description Hein, Mann, Cell 2015
Category members IP bait AKIRIN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AKIRIN2

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring AKIRIN2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AKIRIN2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0010950 positive regulation of endopeptidase activity Database 0.04
Category members GO Category GO:0032755 positive regulation of interleukin-6 production Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0


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