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Query: AKAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AKAP1 0 0.193
AKAP1 0 0.193 -2.003 -0.132 -0.132

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AKAP1 Phosphorylation S192 0.935 1.193 _SIPLECPLS(ph)SPK_
AKAP1 Phosphorylation S193 1.023 1.057 _SIPLECPLSS(ph)PK_
AKAP1 Phosphorylation S149 0.307 0.682 _SES(ph)SGILPNTTDMR_
AKAP1 Phosphorylation S147 0.424 0.589 _S(ph)ESSGILPNTTDM(ox)R_
AKAP1 Phosphorylation S487 0.615 0.512 _SLLSS(ph)PTK_
AKAP1 Ubiquitylation K845 -0.226 0.471 _VK(gl)VDVLR_
AKAP1 Ubiquitylation K842 0.367 _YVDYGGYK(gl)R_
AKAP1 Ubiquitylation K667 -0.208 _LIGK(gl)QGR_

Background Information for AKAP1:


Pubmed-AKAP1 »
Uniprot-AKAP1 »
Biogrid-AKAP1 »
ProteomicsDB-AKAP1 »

Tumorportal-AKAP1 »
COSMIC-AKAP1 »
GenomeRNAi-AKAP1 »
Genecards-AKAP1


Protein-protein Interactions for AKAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RPRD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait APBB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKACB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKACG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKAR2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRSS37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REEP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPP25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFP41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AKAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tudor IPR002999 0.28
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13
Category members RII_binding_1 IPR018459 0.12


Protein complexes (CORUM database) featuring AKAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 519 AMY-1-S-AKAP84-RII-beta complex Database 0


Categories featuring AKAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_437 PID_VEGFR1_2_PATHWAY 0 0.13
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07


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