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Query: AHR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AHR 0 -0.486 -1.080 1.020

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AHR Ubiquitylation K641 -1.506 _QVVVEPQQQLCQK(gl)MK_

Background Information for AHR:





Protein-protein Interactions for AHR

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARNT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AHR

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PAS_fold_3 IPR013655 0.69
Category members bHLH_dom IPR011598 0.32
Category members PAS_fold IPR013767 0.27
Category members PAC IPR001610 0.23
Category members PAS IPR000014 0.23


Protein complexes (CORUM database) featuring AHR

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1211 Ubiquitin E3 ligase (AHR, ARNT, DDB1, TBL3, CUL4B, RBX1) Database 0.05


Categories featuring AHR

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0030522 intracellular receptor signaling pathway Database 0.9
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0001568 blood vessel development Database 0
Category members GO Category GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0009410 response to xenobiotic stimulus Database 0
Category members GO Category GO:0010468 regulation of gene expression Database 0
Category members GO Category GO:0030850 prostate gland development Database 0
Category members GO Category GO:0030888 regulation of B cell proliferation Database 0
Category members GO Category GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0
Category members GO Category GO:0048608 reproductive structure development Database 0
Category members GO Category GO:0048732 gland development Database 0
Category members GO Category GO:0051879 Hsp90 protein binding Database 0


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