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Query: ADD3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADD3 0 4.184 -1.290 1.910 0.268 -0.377 0.481 1.104

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADD3 Phosphorylation S64 0.379 _VTQILQS(ph)PAFREDLECLIQEQMK_
ADD3 Ubiquitylation K280 -0.136 0.353 _IQLQK(gl)VLGPSCK_
ADD3 Phosphorylation S681 0.027 0.143 _IEEVLSPEGSPSKS(ph)PSK_
ADD3 Phosphorylation S42 0.088 _NMS(ph)PDLRQDFNMMEQR_
ADD3 Phosphorylation S677 0.077 -0.026 _IEEVLSPEGS(ph)PSKS(ph)PSK_
ADD3 Phosphorylation S683 0.203 -0.184 _IEEVLSPEGSPSKSPS(ph)K_
ADD3 Phosphorylation S679 -0.270 -0.195 _SPEKIEEVLSPEGSPS(ph)KSPSK_
ADD3 Phosphorylation T12 -0.760 -0.484 _(ac)SSDASQGVITT(ph)PPPPSMPHK_
ADD3 Phosphorylation S423 -0.556 -0.594 _SDVEIPATVTAFSFEDDTVPLS(ph)PLK_
ADD3 Phosphorylation S442 -1.117 _WLNS(ph)PNTYMK_
ADD3 Phosphorylation S478 -2.024 _VS(ph)GGTPIKIEDPNQFVPLNTNPNEVLEK_
ADD3 Phosphorylation T481 -2.024 _VS(ph)GGTPIKIEDPNQFVPLNTNPNEVLEK_
ADD3 Phosphorylation T11 -1.070 _(ac)SSDASQGVIT(ph)TPPPPSM(ox)PHK_
ADD3 Ubiquitylation K21 -0.862 _(ac)SSDASQGVITTPPPPSMPHK(gl)ER_
ADD3 Phosphorylation S673 -0.046 _IEEVLS(ph)PEGSPSKSPSK_

Background Information for ADD3:


Pubmed-ADD3 »
Uniprot-ADD3 »
Biogrid-ADD3 »
ProteomicsDB-ADD3 »

Tumorportal-ADD3 »
COSMIC-ADD3 »
GenomeRNAi-ADD3 »
Genecards-ADD3


Protein-protein Interactions for ADD3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait STAT5A Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ADD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANKRD29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM78A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GBP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLF15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF111 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADD3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldolase_II/adducin_N IPR001303 0.26


Protein complexes (CORUM database) featuring ADD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ADD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0000794 condensed nuclear chromosome Database 1.58
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members Disease phenotype Inherited_congenital_spastic_tetraplegia Inherited congenital spastic tetraplegia Database 0.04
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0


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