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Query: ACD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACD 0 0.448 0.480 -0.150

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACD Phosphorylation S425 1.015 _TPSS(ph)PLQSCTPSLSPR_
ACD Phosphorylation S407 0.499 _SSS(ph)QPSPAICS(ph)APATLTPR_
ACD Phosphorylation S399 -0.567 -0.012 _SSS(ph)QPSPAICSAPATLTPR_
ACD Phosphorylation S111 -0.135 _ELILGSETPSS(ph)PR_

Background Information for ACD:


Pubmed-ACD »
Uniprot-ACD »
Biogrid-ACD »
ProteomicsDB-ACD »

Tumorportal-ACD »
COSMIC-ACD »
GenomeRNAi-ACD »
Genecards-ACD


Protein-protein Interactions for ACD
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait POT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TERF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TERF2IP Cat. description Hein, Mann, Cell 2015
Category members IP bait TINF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TERF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TINF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ACD
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ACD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1204 Rap1 complex Database 0.04
Category members Corum 1197 TRF1-TIN2 complex Database 0
Category members Corum 1198 TIN2 complex Database 0
Category members Corum 1201 TRF1-TIN2 complex Database 0
Category members Corum 138 Telosome complex Database 0


Categories featuring ACD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_884 REACTOME_MEIOTIC_SYNAPSIS 0 7.46
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members GO Category GO:0000723 telomere maintenance Database 6.3
Category members Pathway Pathway_1312 REACTOME_PACKAGING_OF_TELOMERE_ENDS 0 4.09
Category members Pathway Pathway_328 REACTOME_TELOMERE_MAINTENANCE 0 3.74
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0042162 telomeric DNA binding Database 1.23
Category members GO Category GO:0007004 telomere maintenance via telomerase Database 0.98
Category members GO Category GO:0000781 chromosome, telomeric region Database 0.16
Category members GO Category GO:0000783 nuclear telomere cap complex Database 0.11
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001655 urogenital system development Database 0
Category members GO Category GO:0005697 telomerase holoenzyme complex Database 0
Category members GO Category GO:0016233 telomere capping Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0031848 protection from non-homologous end joining at telomere Database 0
Category members GO Category GO:0032202 telomere assembly Database 0
Category members GO Category GO:0032211 negative regulation of telomere maintenance via telomerase Database 0
Category members GO Category GO:0035282 segmentation Database 0
Category members GO Category GO:0051973 positive regulation of telomerase activity Database 0
Category members GO Category GO:0070182 DNA polymerase binding Database 0
Category members GO Category GO:0070198 protein localization to chromosome, telomeric region Database 0


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