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Query: ABI2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABI2 0 -0.934 -0.850 0.640

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABI2 Phosphorylation S227 -0.636 -0.480 _NMAPSQQS(ph)PVR_
ABI2 Phosphorylation S183 -0.737 -0.939 _TTPPTQKPPS(ph)PPMSGK_
ABI2 Ubiquitylation K167 -0.458 _VSTQNMK(gl)MGGLPR_

Background Information for ABI2:


Pubmed-ABI2 »
Uniprot-ABI2 »
Biogrid-ABI2 »
ProteomicsDB-ABI2 »

Tumorportal-ABI2 »
COSMIC-ABI2 »
GenomeRNAi-ABI2 »
Genecards-ABI2


Protein-protein Interactions for ABI2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NHSL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ABI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AMZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf88 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBLC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOMER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0355 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LHX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NHSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIMM50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBXN11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF511 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ABI2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members T_SNARE_dom IPR000727 0.54
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members Abl-interactor_HHR_dom IPR012849 0


Protein complexes (CORUM database) featuring ABI2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABI2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005913 cell-cell adherens junction Database 1.05
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008154 actin polymerization or depolymerization Database 0.47
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0030175 filopodium Database 0.05
Category members GO Category GO:0043010 camera-type eye development Database 0.05
Category members GO Category GO:0070064 proline-rich region binding Database 0.01
Category members Pathway Pathway_912 BIOCARTA_ACTINY_PATHWAY 0 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007611 learning or memory Database 0
Category members GO Category GO:0008093 cytoskeletal adaptor activity Database 0
Category members GO Category GO:0016358 dendrite development Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0018108 peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0030296 protein tyrosine kinase activator activity Database 0


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