Results for the Category
REACTOME_TIE2_SIGNALING
(Pathway_586)
RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
W | |||||||
Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
---|---|---|---|---|---|---|---|---|
PIK3R2 | 1 | 2.740 | -1.180 | 0.269 | 0.348 | |||
KRAS | 1 | -0.510 | 0.620 | 1.031 | 0.887 | |||
KRAS | 1 | -0.510 | 0.620 | 0.246 | -0.346 | |||
NRAS | 1 | 1.810 | -0.720 | 0.246 | -0.346 | |||
PIK3CB | 0 | -1.390 | 2.350 | |||||
PIK3CB | 0 | -0.710 | 1.450 | |||||
SOS1 | 0 | 0.500 | -0.620 | -0.570 | ||||
PIK3CA | 0 | |||||||
PIK3R1 | 0 | 1.910 | -1.220 | -0.441 | 0.147 | |||
HRAS | 0 | 1.470 | -0.520 | |||||
GRB2 | 0 | -0.240 | 0.300 | -1.021 | 0.057 | 0.906 |
Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
---|---|---|---|---|---|
GRB2 | Ubiquitylation | K10 | 0.146 | _YDFK(gl)ATADDELSFK_ | |
GRB2 | Ubiquitylation | K20 | -0.078 | _ATADDELSFK(gl)R_ | |
GRB2 | Ubiquitylation | K69 | -0.362 | 0.641 | _AK(gl)AEEMLSK_ |
GRB2 | Ubiquitylation | K76 | 0.754 | _AEEMLSK(gl)QR_ | |
GRB2 | Ubiquitylation | K109 | 0.381 | -0.002 | _FGNDVQHFK(gl)VLR_ |
HRAS | Ubiquitylation | K170 | -1.005 | _K(gl)LNPPDESGPGCMSCK_ | |
KRAS | Ubiquitylation | K128 | 1.528 | 1.433 | _TVDTK(gl)QAHELAK_ |
KRAS | Ubiquitylation | K235 | 0.591 | 0.087 | _TVDTK(gl)QAQDLAR_ |
KRAS | Ubiquitylation | K254 | -0.450 | -0.156 | _SYGIPFIETSAK(gl)TR_ |
NRAS | Ubiquitylation | K128 | 1.528 | 1.433 | _TVDTK(gl)QAHELAK_ |
PIK3CA | Ubiquitylation | K864 | 0.390 | 0.588 | _NSHTIM(ox)QIQCK(gl)GGLK_ |
PIK3CA | Ubiquitylation | K868 | 0.204 | 0.651 | _NSHTIM(ox)QIQCKGGLK(gl)_ |
PIK3CA | Ubiquitylation | K974 | -0.273 | _GAQECTK(gl)TREFER_ | |
PIK3CB | Ubiquitylation | K1044 | 0.990 | _SEEEALKQFKQK(gl)_ | |
PIK3R2 | Phosphorylation | S262 | -2.237 | _APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_ | |
PIK3R2 | Phosphorylation | S263 | -2.237 | _APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_ | |
PIK3R2 | Ubiquitylation | K500 | -0.189 | _IFEEQGQTQEK(gl)CSK_ | |
PIK3R2 | Ubiquitylation | K541 | -0.609 | _TK(gl)LEQQLR_ | |
PIK3R2 | Ubiquitylation | K564 | -0.431 | -1.022 | _MNSLK(gl)PDLMQLR_ |
SOS1 | Phosphorylation | S1082 | 0.278 | _IPESETESTASAPNS(ph)PR_ | |
SOS1 | Phosphorylation | S1166 | 0.097 | -0.094 | _RPESAPAES(ph)SPSK_ |
.
© Copyright Svejstrup Laboratory 2015