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BIOCARTA_NFKB_PATHWAY
(Pathway_1057)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
TNFRSF1A 0 -0.590 0.470
MAP3K1 0 0.750 -1.270
IKBKB 0 0.400 0.610
NFKB1 0 0.720 -0.810
TNFAIP3 0 0.760 -0.500
MAP3K7 0 -1.120 1.140 -1.048
RIPK1 0 -0.190 0.440
RELA 0 -1.130 1.600 0.793
CHUK 0 -0.480

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
IKBKB Ubiquitylation K106 0.253 _K(gl)YLNQFENCCGLR_
IKBKB Phosphorylation S672 0.670 0.244 _GPVSGS(ph)PDSMNASR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
RIPK1 Ubiquitylation K642 -0.431 _EGIK(gl)GATVGK_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TNFRSF1A Ubiquitylation K242 -0.111 _SK(gl)LYSIVCGK_


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